1 Star 0 Fork 0

didipostman / CrisprCas9

Gitee — Enterprise-level DevOps R&D management platform
Join Gitee
Clone or download
Cancel
Notice: Creating folder will generate an empty file .keep, because not support in Git
Loading...
README.md

Crispr Cas 9

Spring Batch + algorithm of DNA pattern recognition here I used Karp Rabin = how Crispr Cas 9 function

A Java IT Model for DNA damage repair and Genome sequencing solution to fight Covid19 and other diseases = how Crispr Cas 9 function Author: Wadï Mami 17/06/2020 email: didipostman77@gmail.com

the Architecture sequence diagram describing how Spring Batch function and the dependency between Spring Batch Core and item reader, item Processor and item Writer + karp Rabin ( or any other pattern recognition algorithm) = How CRISPR Cas9 function see picture below

alt text

I cant go further with it may be someone find it useful and continue.

Here More Explanation

A model for drugs discovery against Covid19 cancer diabète and many diseases

Author : Wadï Mami

Publication date : 26/04/2021

Email : wmami@steg.com.tn

Abstract

I will try to present my model for drugs discovery against Covid19 Cancer diabete and many other diseases. In fact my IT model can be used to explain how Crispr Cas9 Works and then creating drugs based on that model may could be possible.

CRISPR-Cas9

CRISPR-Cas9 was adapted from a naturally occurring genome editing system in bacteria. The bacteria capture snippets of DNA from invading viruses and use them to create DNA segments known as CRISPR arrays.The CRISPR arrays allow the bacteria to "remember" the viruses (or closely related ones). If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays to target the viruses' DNA. The bacteria then use Cas9 or a similar enzyme to cut the DNA apart, which disables the virus.

The Model

the Architecture sequence diagram describing how Spring Batch[1] function and the dependency between Spring Batch Core and item reader, item Processor and item Writer + karp Rabin ( or any other pattern recognition algorithm) = How CRISPR Cas9 works see picture below

alt text

In fact The bacteria capture snippets of DNA from invading viruses and use them to create DNA segments known as CRISPR arrays. DNA = input file or database see sequence diagram above ( Spring Batch ---> ItemReader returns item processed by ItemProcessor which returns transformed items = DNA segments known as CRISPR arrays.

The bacteria then use Cas9 or a similar enzyme to cut the DNA apart, which disables the virus. Look Spring Batch ---à ItemWriter (write(transformed items))

Here we didn’t see Karp Rabin but following the template source code

you will find a DNASequence_Processor class that implements itemProcessor and use Karp Rabin Algorithm.

Conclusion

Spring Batch + Karp Rabin = how CRISPR Cas9 works is my IT theoretical model may be it could be interesting and useful for drugs discovery. The model is an idea that had been haunting me since 2012. I share it with you. I can’t go further with it, may be you find it useful interesting and continue developement. The model is under MIT License

Repository Comments ( 0 )

Sign in for post a comment

About

Spring Batch + Karp Rabin = How Crispr Cas 9 function expand collapse
Java
MIT
Cancel

Releases

No release

Contributors

All

Activities

load more
can not load any more
Java
1
https://gitee.com/didipostman/CrisprCas9.git
git@gitee.com:didipostman/CrisprCas9.git
didipostman
CrisprCas9
CrisprCas9
main

Search

181749 a2d7925e 1850385 181749 9f8568a7 1850385