Dex 65536

android update project -p ./Dex65536
android update project -p ./Lib
cd Dex65536
ant clean debug install run

Dex65536/custom_rules.xml
Dex65536/pathtool.jar

android update project -p .

public class App extends Application {

	@Override
	public void onCreate() {
		super.onCreate();
		dexTool();
	}

	/**
	 * Copy the following code and call dexTool() after super.onCreate() in
	 * Application.onCreate()
	 * <p>
	 * This method hacks the default PathClassLoader and load the secondary dex
	 * file as it's parent.
	 */
	@SuppressLint("NewApi")
	private void dexTool() {

		File dexDir = new File(getFilesDir(), "dlibs");
		dexDir.mkdir();
		File dexFile = new File(dexDir, "libs.apk");
		File dexOpt = new File(dexDir, "opt");
		dexOpt.mkdir();
		try {
			InputStream ins = getAssets().open("libs.apk");
			if (dexFile.length() != ins.available()) {
				FileOutputStream fos = new FileOutputStream(dexFile);
				byte[] buf = new byte[4096];
				int l;
				while ((l = ins.read(buf)) != -1) {
					fos.write(buf, 0, l);
				}
				fos.close();
			}
			ins.close();
		} catch (Exception e) {
			throw new RuntimeException(e);
		}

		ClassLoader cl = getClassLoader();
		ApplicationInfo ai = getApplicationInfo();
		String nativeLibraryDir = null;
		if (Build.VERSION.SDK_INT > 8) {
			nativeLibraryDir = ai.nativeLibraryDir;
		} else {
			nativeLibraryDir = "/data/data/" + ai.packageName + "/lib/";
		}
		DexClassLoader dcl = new DexClassLoader(dexFile.getAbsolutePath(),
				dexOpt.getAbsolutePath(), nativeLibraryDir, cl.getParent());

		try {
			Field f = ClassLoader.class.getDeclaredField("parent");
			f.setAccessible(true);
			f.set(cl, dcl);
		} catch (Exception e) {
			throw new RuntimeException(e);
		}
	}

}

<application
    android:name="com.github.mmin18.dex65536.App"
    android:icon="@drawable/ic_launcher"
    android:label="@string/app_name" >

cd /YourProject
ant clean debug install run