diff --git a/sig/sig-python-modules/sig-info.yaml b/sig/sig-python-modules/sig-info.yaml
index 27df9b3b91c267b8a169eea8510c0478ee2bb123..4aa73bd8e6d8b39fd4420b7b60d1d348f82bf025 100644
--- a/sig/sig-python-modules/sig-info.yaml
+++ b/sig/sig-python-modules/sig-info.yaml
@@ -1267,6 +1267,7 @@ repositories:
   - src-openeuler/python-bitarray
   - src-openeuler/python-justbases
   - src-openeuler/python-krb5
+  - src-openeuler/python-mrcfile
   committers:
   - gitee_id: randy1568
     name: lipeng Yuan
diff --git a/sig/sig-python-modules/src-openeuler/p/python-mrcfile.yaml b/sig/sig-python-modules/src-openeuler/p/python-mrcfile.yaml
new file mode 100644
index 0000000000000000000000000000000000000000..7b79166c118d1ddadad6dca453f9341a64be3259
--- /dev/null
+++ b/sig/sig-python-modules/src-openeuler/p/python-mrcfile.yaml
@@ -0,0 +1,7 @@
+name: python-mrcfile
+upstream: https://github.com/ccpem/mrcfile
+description: mrcfile is a Python implementation of the MRC2014 file format, which is used in structural biology to store image and volume data.
+branches:
+- name: master
+  type: protected
+type: public