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diff --git a/bcftools-1.19 b/bcftools-1.19
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--- a/bcftools-1.19
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-Subproject commit 19937cafc1f234a6033f3338153a4707e139eab7
diff --git a/bcftools.spec b/bcftools.spec
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--- a/bcftools.spec
+++ b/bcftools.spec
@@ -1,6 +1,6 @@
 Name:    bcftools
-Version: 1.19
-Release: 2
+Version: 1.21
+Release: 1
 Summary: Tools for genomic variant calling and manipulating VCF/BCF files
 
 # This software is available under a choice of one of two licenses,
@@ -61,6 +61,9 @@ autoconf
 
 
 %changelog
+* Thu Nov 07 2024 jinzhiguang <jinzhiguang@kylinos.cn> - 1.21-1
+- update to 1.21
+
 * Sat Mar 23 2024 guoyizhang <kuoi@bioarchlinux.org> - 1.19-2
 - rebuild for htslib version updated.